6-(Methoxycarbonyl)indazole-4-boronic Acid Pinacol Ester - Names and Identifiers
Name | methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate
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Synonyms | 6-(Methoxycarbonyl)indazole-4-boronic Acid Pinacol Ester methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate
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CAS | 1527007-77-7
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6-(Methoxycarbonyl)indazole-4-boronic Acid Pinacol Ester - Physico-chemical Properties
6-(Methoxycarbonyl)indazole-4-boronic Acid Pinacol Ester - Upstream Downstream Industry
6-(Methoxycarbonyl)indazole-4-boronic Acid Pinacol Ester - Introduction
methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate is an organic compound, commonly known as methyl formate 4-(4,4,5,5-tetramethyl-1,3, 2-dioxaboran-2-yl)-1H-indazole-6-carboxylic acid ester.
Nature:
-Appearance: It is a white solid.
-Melting point: Its melting point is about 100-105°C.
-Solubility: It has good solubility in some organic solvents (such as dichloromethane, dimethyl sulfoxide and ether), but has low solubility in water.
Use:
-It can be used as a reagent and intermediate in organic synthesis.
-It has strong electrophilicity, so it can be used as an electrophile to participate in different types of reactions, such as boronation, carboxylic acid activation and substitution reactions.
Method:
methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate can generally be prepared by the following reaction:
First, 4-(4,4,5,5-tetramethyl-1,3, 2-dioxaboran-2-yl)-Lh-indazole-6-carboxylic acid reacts with methanol to give methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate of methyl formate.
Safety Information:
Regarding the safety of methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate, we need to understand its toxicity and danger. When using the compound, follow appropriate laboratory safety practices and consult its safety data forms or relevant literature to discuss the use of appropriate personal protective equipment.
Last Update:2024-04-09 21:54:55